Table 2.

Anti-Spe antibodies in patients with severe and nonsevere invasive group A streptococcal infections

ELISA antigenLevel of anti-Spe antibodies in plasma (mean ELISA titer ± SEM) for:
Healthy individuals (n = 20)All invasive cases (n = 33)Severe invasive cases (n = 21)Nonsevere invasive cases (n = 12)
SpeA114 ± 1472 ± 6  (P < 0.003a)67 ± 8  (P < 0.002a)80 ± 10  (P < 0.025a; P = 0.15b)
SpeB60 ± 628 ± 6  (P < 0.0002a)23 ± 7  (P < 0.0001a)37 ± 8  (P < 0.004a; P = 0.111b)
SpeF153 ± 1690 ± 10  (P < 0.001a)83 ± 13  (P < 0.0008a)103 ± 15  (P < 0.016a; P = 0.15b)
  • a Versus results for age-matched healthy individuals.

  • b Versus results for severe invasive cases.