Table 3.

Effect of the rpoE mutation onS. typhimurium immunogenicitya

Immunization routeDose (CFU)Protection (no. of survivors/no. challenged)
Oral8.75 × 109 0/5
9.63 × 107 0/5
1.0 × 106 0/5
i.v.1.11 × 106 2/5
1.0 × 104 2/5
  • a Mice were immunized as indicated; 28 days later they were challenged orally with 2 × 108CFU of SL1344. Mice were observed for 6 weeks, and the number of deaths were recorded.