Table 2.

Effect of the rpoE mutation on S.  typhimurium virulencea

StrainGenotypeLD50
Orali.v.
SL1344Wild type1.20 × 106 <10
BRD915 htrA >1010 5.5 × 105
GVB311 rpoE >1010 1.24 × 107
  • a Groups of five mice were challenged with different doses of each strain of S. typhimuriumby the route indicated, and the deaths were recorded for 6 weeks.