Table 2.

Effect of the rpoE mutation on S.  typhimurium virulencea

StrainGenotypeLD50
Orali.v.
SL1344Wild type1.20 × 106<10
BRD915htrA>10105.5 × 105
GVB311rpoE>10101.24 × 107
  • a Groups of five mice were challenged with different doses of each strain of S. typhimuriumby the route indicated, and the deaths were recorded for 6 weeks.