Table 3.

Level of antibodies measured by ELISA during the immunization protocola

Antibody against:Mean antibody level (OD405) ± SD
NonimmunizedInjected with:
Saponin (control)Saponin + GK-1
1st dose2nd dose1st dose2nd dose
GK-10.129 ± 0.0070.146 ± 0.0050.164 ± 0.0100.164 ± 0.020b 0.190 ± 0.020b
T. crassicepsantigens0.150 ± 0.010.189 ± 0.0060.230 ± 0.0270.247 ± 0.105b 0.431 ± 0.131b
  • a Groups of 10 mice each immunized and tested 2 weeks after each immunization The serum antibody levels against GK-1 and T. crassiceps cysticercal antigens were determined by ELISA in GK-1-immunized, nonimmunized, and saponin-injected mice. Levels of murine antibodies raised during the course of immunization with GK-1 peptide are shown.

  • b Considered statistically significant at P < 0.05.