Table 3.

Summary of in vivo expression of C. albicans ACT1 and SAP1 to SAP7 mRNAs inCandida culture-negative control, Candidacarrier, and oral candidiasis study populations

Study populationHIV statusaActinbSAPgene expressionb
SAP1SAP2SAP3SAP4SAP6SAP7
Total no. of controls positivec NDd  00 00 00
Candida carriers
 AND++
 BND++
 CND++++
 DND+++
 END+++
 FND+++
 GND+++
 HND++++
  Total no. positiveND 80 60 82
Oral candidiasis  patients
 A++++++
 B+++
 C++++
 D+++++++
 E++++
 F+++++
 G+++++
 H++++
 I+++++++
 J+++++
  Total no. positive6102106106
  • a +, HIV-seropositive patient; −, HIV-seronegative patient.

  • b +, presence of mRNA detected by RT-PCR; −, absence of mRNA determined by RT-PCR.

  • c Seven Candida culture-negative controls were studied.

  • d ND, not determined.