Table 3.

Serological characteristics of initial and passagedC. neoformans strains

IsolateIF patternaEndpoint (μg/ml)
MAb 12A1MAb 13F1IFAgglutination
PBS2H1PBS2H1PBS2H1PBS2H1
62066
 P0AAAA0.10.16.256.25
 P1AAAA0.1<0.0112.512.5
 P2AAAA0.10.112.512.5
 P3NDb ANDAND0.1ND0.1
24067
 P0AAPP<0.01<0.0111
 P1AAPP<0.01<0.010.51.9
 P2AAPP<0.01<0.011.91.9
 P3AAPP<0.01<0.011.91
 P4AAPP<0.01<0.011.91
 P5AAPP<0.01<0.0111
C3D
 P0AAAA<0.01<0.010.50.5
 P1AAAA0.1<0.010.250.25
 P2ANDAND<0.01ND0.5ND
62066c
 P0AAAA0.10.16.256.25
 P1AAAA113.97.8
C3Dc
 P0AAAA<0.01<0.010.50.5
 P1AAAA10.10.51.9
  • a A, annular; P, punctate. Results are for isolated passaged in mice given PBS or 2H1, as indicated.

  • b ND, not done.

  • c Passaged in mice by the organ homogenate method.