Table 1.

B. malayi infection in nude, RAG1, SCID, TCRβδ, μMT, and C57BL/6J mice

Mouse genotype (n = 5/ group)Worm burden (%)a
Expt 1Expt 2
RAG135.6 ± 1319.6 ± 6
SCID31.6 ± 715.2 ± 7
μMT28 ± 911.1 ± 8
Nude15.8 ± 123.3 ± 5
TCRβδ10.8 ± 132.6 ± 4
+/+0 ± 00 ± 0
  • a Values represent the mean worm burdens at 6 weeks as percentages of L3 larvae injected ± the standard deviation for the groups in two different experiments. The yields of adult worms in RAG1, SCID, and μMT mice were significantly different from those in nude, TCRβδ, and C57BL/6J mice (P < 0.05).