Table 2.

B. malayi L4 larval development in nude, RAG1, SCID, TCRβδ, μMT, and C57BL/6J mice

Mouse genotype (n = 5/ group) Yield of adult worms (%)a
μMT48.8 ± 13
SCID33.2 ± 15
RAG130.4 ± 10
+/+23.6 ± 10
Nude12.2 ± 11
TCRβδ5.5 ± 4
  • a Values represent mean larval yields at 2 weeks as percentages of L3 larvae injected ± the standard deviation for the groups. The yields of adult worms in the μMT, SCID, and RAG1 mice were significantly different from those in the nude and TCRβδ mice (P < 0.05).