TABLE 2.

Protection elicited by rabbit dPNAG-DT sera against various S. aureus strains in the murine bacteremia model in comparison to NRS

S. aureus strainChallenge doseMean CFU/ml blood ± SEMa% ReductionP valuea
NRSdPNAG-DT sera
108332.5 × 1061,925 ± 588446 ± 52770.04
Becker1.8 × 106184 ± 3.582 ± 2.5550.034
COL3.1 × 105229 ± 2.1105 ± 254<0.001
MN82.5 × 1079,821 ± 3,545914 ± 167910.045
  • a P value determined by unpaired t test. SEM, standard error of the mean.