TABLE 2.

Proportion of mice with positive blood cultures (≥ 2 CFU/ml) after infection under the indicated conditions with different strains of S. aureus

S. aureus strain and injection routeTime postinfection (h)No. of mice with positive blood cultures/total no.
WTComplementedΔica
Newman, i.v.28/88/86/8
48/88/86/8
10833, i.v.28/88/85/8
48/88/84/8a
MN8, i.v.28/88/83/8b
48/88/81/8c
Newman, i.v./CSAd2NDe8/84/8a
4ND8/83/8b
Newman, i.p.2ND8/84/8a
4ND8/84/8a
  • a Significantly different from the value obtained for the WT strain (P = 0.038 by Fisher's exact test).

  • b Significantly different from the value obtained for the WT strain (P = 0.013 by Fisher's exact test).

  • c Significantly different from the value obtained for the WT strain (P = 0.0007 by Fisher's exact test).

  • d CSA, Columbia salt agar used to prepare the inoculum.

  • e ND, not done.