TABLE 2.

CFU in nasal washes, nasal tissues, brains, and lungs of mice inoculated i.n.

ExptInoculumNo. of miceLog10 CFU ina:
StrainDose (log10)Nasal washNasal tissueOlfactory bulbbBrainbLungb
1TIGR45.7843.55 (0.35)2.63 (0.06)1.0 (0.00)c<1.02.66 (0.39)
2EF30307.2133.98 (0.07)6.63 (0.16)5.50 (1.60)2.68 (0.47)2.1 (0.1)
3BG73226.3333.17 (0.16)3.93 (0.08)2.37 (0.47)1.34 (0.04)ND
4BG73226.9234.03 (1.48)5.78 (1.88)2.53 (0.07)1.63 (0.048)<1.6c
5L820166.6952.28 (0.23)2.27 (0.32)<1.01.5 (0.50)<1.6
6L820166.6652.78 (0.30)3.81 (0.31)<1.0<1.0<1.6
7L820166.8034.067 (0.35)4.953 (0.10)0.55 (0.25)0.30 (0.00)2.67 (0.07)
  • a Mean (standard error). The values indicate the total numbers of CFU in the tissues.

  • b The values for the average numbers of CFU in the olfactory bulb, the remainder of brain, and the lung are averages for positive mice only. ND, not done.

  • c <1.0 or <1.6 log10 CFU are the limits of detection. These values are given when there were no colonies in the tissue of any of the inoculated mice.