TABLE 1.

Odds ratios for colonization for each twofold increase in concentration of antibody against PspA, PsaA, or CWPSa

AntigenUnivariate OR (95% CI)bP value
PspA0.76 (0.64, 0.91)0.004
PsaA0.82 (0.70, 0.96)0.016
CWPS0.63 (0.44, 0.91)0.005

  • ↵a Colonization was indicated by the presence of ≥1 CFU detectable in nasal wash fluid. Data were obtained from conditional logistic regression analysis and grouped by challenge strain. In a multivariate model, only PspA data remained significant.

  • ↵b OR, odds ratio; CI, confidence interval.