Table 1.

Number of Lyme arthritis patients with positive responses to B. burgdorferi antigens

Time of responseaAntigenNo. (%) of patients with positive response
IgMIgG
EMbEarly arthralgia/arthritisMaximal arthritisEMEarly arthralgia/arthritisMaximal arthritis
EarlyOspC20 (80)10 (40)4 (16)17 (68)21 (84)20 (80)
P358 (35)9 (36)4 (16)21 (84)20 (83)23 (92)
P3717 (68)12 (48)7 (28)14 (56)16 (67)20 (80)
P4117 (68)10 (40)6 (24)19 (76)19 (79)24 (96)
Weeks laterOspE17 (74)13 (54)13 (48)1 (4)10 (40)18 (72)
OspF8 (35)11 (46)8 (35)6 (25)14 (58)20 (80)
P3912 (48)9 (36)6 (24)9 (36)18 (72)25 (100)
P938 (32)7 (28)5 (20)4 (16)14 (56)22 (88)
Months to years laterOspA4 (16)0 (0)8 (35)5 (20)3 (12)16 (64)
OspB3 (12)0 (0)7 (28)3 (12)6 (24)16 (64)
  • a Based on the timing of the IgG responses of the majority of patients.

  • b EM, erythema migrans.