Table 4.

Symptoms and colonization of SC602 vaccinees and unvaccinated control subjects after challenge with S. flexneri 2a strain 2457T

CharacteristicControlsVaccinees
No. of volunteers77
Volunteers excreting S. flexneri 2a66
Volunteers with diarrhea63
Mean no. of diarrheal stools (range)11 (6–20)4 (2–6)
Volunteers with dysentery40
Volunteers with fever (mean temp)6 (102.7°F)0a
Volunteers with severe shigellosis60a
  • a P = 0.005, vaccinees versus controls.