Table 1.

Summary of phase 1 trial of S. flexneri 2a SC602 vaccination

GroupaS. flexneri 2a SC602 ingested (CFU)No. of vaccinees displaying:
Day 0Day 3DiarrheabFeverc
11.6 × 102NAd00
21.6 × 1043.2 × 10401
32.4 × 1051.2 × 10501
42.0 × 106NA00
52.3 × 107NA01
62.9 × 108NA22
  • a Three volunteers per group.

  • b Two or more grade 3 stools totaling at least 200 ml or one grade 3 stool of 300 ml within 48 h.

  • c At least 100.5°F.

  • d NA, not applicable.