Table 1.

Alignment of major ospC groups withospC alleles identified by SSCP analysis

Major ospC groupospCalleleGenBank accession no.aNo. of the indicatedospC group in isolates fromb:
TicksHuman skinSecondary sites of human infection
A1AF029860172321
B2AF02986117194
C3AF0298621130
D4AF0298631010
E5, 7AF029864610
F6AF029865900
G8AF029867570
H9AF029868760
I10AF029869193
J11, 18AF029870370
K12, 13AF02987163216
LL42899200
M14U01892130
N15L42899130
OX84778010
PcU91796100
QcU91790100
RcU91791200
ScU91793100
T16AF065143010
U17AF065144020
  • a A single GenBank sequence for each type is given as an example. The complete list of sequences is given in reference 40.

  • b The number of each major ospCgroup observed. This includes both SSCP data and data from the literature, including GenBank.

  • c B. burgdorferi sensu stricto groups P through S are found only in Europe. Groups R and S are excluded from the analysis because nearly identical ospCalleles are found in B. afzelii and B. garinii, showing that these groups were recently created by cross-species transfer.