Table 1.

Binding of H. influenzae strains to Chang epithelial cells

StrainPhenotypeBinding (CFU/well)a (% of inoculum)
EaganType b, clinical isolate3.1 × 106 ± 0.4 × 106 (11)b
H229Eagan, OapA 1.2 × 105 ± 0.2 × 105 (1.1)
RdUnencapsulated type d clinical isolate4.1 × 106 ± 0.6 × 106 (13)b
H209Rd, OapA, Kanr 1.4 × 105 ± 0.2 × 105 (1.5)
H217H209, OapA+, Kans 3.4 × 106 ± 0.4 × 106 (11.3)b
H233Nontypeable, clinical isolate6.0 × 106 ± 1.0 × 106 (20)b
H487H233, Oap, Kanr 7.9 × 105 ± 1.3 × 105 (6.5)
  • a Mean ± standard deviation of at least five separate experiments done in triplicate.

  • b P < 0.01 by two-tailed unpaired t test compared to the corresponding OapA mutant.