TABLE 2

Genes downregulated in CP1ΩagrB compared to wild-type CP1

Locus tagGenBank accession no.GenePutative gene productFold changeq value (%)
CP4_0126AM596_00605Glucose kinase−8.530.00
CP4_0211AM596_01000colAMicrobial collagenase−3.077.77
CP4_0349AM596_01670Transcriptional regulator−2.0510.72
CP4_0398AM596_01900Pyruvate kinase−2.227.77
CP4_0473AM596_02265Phosphopentomutase−12.790.00
CP4_0573AM596_02740Signal peptidase I−4.177.77
CP4_0575AM596_02750Sortase, Srtb family−4.051.72
CP4_1164AM596_05510UBA/TS-N domain-containing protein−2.0710.72
CP4_1297AM596_06115dhaBGlycerol dehydratase, large subunit−6.2510.72
CP4_1298AM596_06120dhaCGlycerol dehydratase, medium subunit−6.110.00
CP4_1300AM596_06130dhaFGlycerol dehydratase reactivation factor, large−25.470.00
CP4_1301AM596_06135Glycerol dehydratase reactivation factor, small−10.381.72
CP4_1302AM596_06140ATP:cob(I)alamin adenosyltransferase−10.130.00
CP4_1303AM596_06145dhaGDhaG protein−7.330.00
CP4_1304AM596_06150dhaT1,3-Propanediol dehydrogenase−6.044.08
CP4_1328AM596_06270Conserved hypothetical protein−4.3211.51
CP4_1396AM596_06575Aminodeoxychorismate synthase, component I−2.267.77
CP4_1422AM596_06695Iron chelate ABC transporter solute-binding−2.262.92
CP4_1497AM596_07060Conserved hypothetical protein−4.244.08
CP4_1531AM596_07215Coenzyme A substrate-specific enzyme activase−2.1910.72
CP4_1720AM596_08080Sodium:neurotransmitter symporter family−3.012.92
CP4_1915AM596_09015Lipoprotein, putative−13.790.00
CP4_1916AM596_09020agrBAccessory gene regulator protein B−35.450.00
CP4_2070AM596_09775Ribosomal protein S16−2.557.77
CP4_2113AM596_09990Fe-S oxidoreductase−2.844.64
CP4_2294AM596_10880Adenine phosphoribosyltransferase−2.001.72
CP4_2457AM596_11635Deoxyribose-phosphate aldolase−3.800.00
CP4_2753AM596_13080Na+/H+ antiporter family protein−4.0710.72
CP4_2949AM596_14020Nucleoside permease Nupx−6.954.64
CP4_3445AM596_16310Putative radical SAM domain-containing protein−15.750.00
CP4_3449AM596_16320netBNecrotic enteritis toxin B−27.030.00
CP4_3450AM596_16325netHRicin-type beta-trefoil domain protein−29.240.00