Table 5.

Comparison of serum, saliva, and cervical mucus IgA1 and IgG antibody levels to N. gonorrhoeae MS11 and infecting isolates in patients with cervical infections and patients with cervical and rectal infections

SampleIg isotypeVisitMedian antibody level (% of total Ig) (range [n])
Anti-MS11 antibodiesAnti-cervical isolate antibodies
Cervical infectionCervical and rectal infectionCervical infectionCervical and rectal infection
Cervical mucusIgA110.00 (0.00–0.21 [11])0.16 (0.00–0.45 [6])0.00 (0.00–0.08 [12])0.00 (0.00–0.15 [6])
IgA120.03 (0.00–1.12 [7])0.00 (0.00–0.07 [6])0.07 (0.00–1.97 [7])0.08 (0.00–0.73 [6])
IgG10.57 (0.00–12.40 [11])0.85 (0.41–1.55 [6])0.09 (0.00–0.94 [11])0.32a (0.08–2.43 [6])
IgG20.74 (0.03–2.90 [7])0.71 (0.00–0.86 [5])0.00 (0.00–0.07 [7])0.37b (0.01–1.39 [5])
SalivaIgA110.06 (0.00–0.42 [7])0.04 (0.00–0.09 [5])0.01 (0.00–0.07 [8])0.00 (0.00–0.03 [6])
IgA120.03 (0.00–0.24 [5])0.03 (0.01–0.05 [4])0.01 (0.01–0.20 [5])0.01 (0.00–0.02 [5])
IgG10.12 (0.00–1.58 [8])0.30 (0.00–0.40 [5])0.26 (0.00–1.91 [8])0.06 (0.00–0.46 [6])
IgG20.47 (0.00–1.77 [5])0.00 (0.00–0.59 [3])0.15 (0.00–4.30 [5])0.00 (0.00–0.43 [5])
SerumIgA110.01 (0.00–0.02 [12])0.02 (0.01–0.05 [7])0.01 (0.00–0.06 [12])0.01 (0.00–0.09 [7])
IgA120.01 (0.00–0.02 [7])0.02 (0.01–0.05 [6])0.01 (0.01–0.02 [7])0.01 (0.00–0.08 [6])
IgG10.25 (0.14–1.41 [12])0.28 (0.20–1.13 [7])0.21 (0.06–3.42 [12])0.77 (0.00–0.94 [7])
IgG20.28 (0.13–0.58 [7])0.33 (0.25–1.29 [6])0.25 (0.19–0.85 [7])0.46 (0.08–0.79 [6])
  • a P = 0.0782 compared with patients with cervical infection.

  • b P = 0.0303 compared with patients with cervical infection.