Table 2.

Total Ig levels in female genital tract secretions from noninfected subjects and patients with STD

SampleIg isotypeMedian Ig level (μg/ml) (range) [ n ])
No current infectionCurrent infection witha:
Tva and/or CtrNgoNgo, Tva, and/or Ctr
Cervical mucusIgA146 (1–227 [18])67 (5–1,150 [13])68 (10–630 [10])33 (1–129 [7])
IgA230 (2–140 [17])37 (2–356 [12])13 (0–196) [8])14 (1–67 [7])
IgG128 (2–2,732 [18])162 (20–950 [13])116 (5–1,353 [11])177 (38–1,891 [7])
IgM17 (1–111 [17])26 (0–1,080 [13])60 (8–116 [9])13 (3–51 [8])
Vaginal washIgA14.9 (0.2–70.0 [17])1.8 (0.1–20.7 [13])4.6 (0.6–39.4 [10])8.6 (1.1–35.8 [8])
IgA24.2 (0.2–44.6 [17])2.7 (0.0–28.5 [13])3.1 (0.0–11.4 [10])2.0 (0.0–19.9 [8])
IgG18.3 (1.0–218.9 [17])25.3 (0.7–57.6 [13])12.3 (3.1–72.2 [12])11.3 (4.2–171.7 [8])
IgM0.6 (0.0–13.7 [10])0.5 (0.0–3.7 [9])1.9 (0.1–2.6 [3])0.6 (0.1–0.8 [3])
  • a Ctr, C. trachomatis; Tva, T. vaginalis; Ngo, N. gonorrhoeae.