Table 4.

H. ducreyi hemolysin is cytotoxic to mononuclear cells but not PMNs

StrainNormalized LDH releasea from:
Mononuclear cellsPMNs
350000.00 ± 0.020.26 ± 0.22
35000ΔAPC0.12 ± 0.030.41 ± 0.06
35000ΔAPC(pLSSK)0.00 ± 0.110.32 ± 0.25
35000ΔAPC(pLSBA+2)1.52 ± 0.110.18 ± 0.20
35000ΔAPC(pLS384-2)44.53 ± 4.460.85 ± 0.14
35000ΔAPC(pLSB+)0.00 ± 0.250.15 ± 0.22
  • a Values represent normalized LDH release and are the average of quadruplicate samples ± standard error. The results of a typical experiment are shown; the experiment was repeated twice with mononuclear cells and three times with PMNs with similar results.