Table 1.

Effect of CPA on peripheral blood leukocyte numbers in pigs

Circulating leukocyte typeNo. of cells/mm31-aMean % reductionbP value
Baseline+CPA
Neutrophils8,079 ± 1,5181,101 ± 1,013870.009
Monocytes678 ± 1796 ± 6990.029
Lymphocytes6,498 ± 9413,360 ± 607490.031
Total15,425 ± 1,5873,650 ± 77776<0.001
  • a Leukocyte numbers are presented as the mean ± standard error for four pigs. Baseline values were determined before treatment with CPA and 4 days prior to infection withH. ducreyi. Values for post-CPA administration were determined on the day of infection with H. ducreyi and 4 days after beginning CPA treatment.

  • b % reduction = [(baseline − CPA)/baseline] × 100.