Table 3.

Mean toxin A-specific serum and mucosal antibody titers as measured by ELISAa

ImmunogenSerumLung washNasal wash
14CDTA-TETC5,405 ± 3,79348 ± 453 ± 4
14CDTA-TETC + LT43,785 ± 34,9041,275 ± 1,55586 ± 71
14CDTA-TETC + LTR7240,724 ± 17,285853 ± 71140 ± 19
  • a Samples were taken after three i.n. doses (day 47) of 14CDTA-TETC given with or without LTR72 adjuvant. For serum, specific total Ig levels are shown, while specific IgA titers were measured in lung and nasal lavage samples. Mean titers ± SDs are shown for five mice per group.