Table 3.

Phylogenetic distribution of iroNE. coli -homologous DNA sequencea

Dot Blot scoreb% (no.) of isolatesc
Group 1Group 2Group 3Group 4Group 5Group 6Group 7
043 (6)20 (1)5 (1)7 (1)10 (2)d 6 (2)e 7 (4)f
1+ 43 (6)0 (0)50 (10)27 (4)57 (12)g 40 (14)g 46 (26)g
2+ 14 (2)80 (4)45 (9)67 (10)33 (7)g 54 (19)h 46 (26)i
Any+ 57 (8)80 (4)95 (19)93 (14)90 (19)d 94 (33)e 93 (52)f
  • a Group 1, 14 unique fecal isolates previously established not to contain pap, hly, or cnf-1 and therefore most representative of nonpathogenic strains (19); group 2, 5 unique fecal isolates possessing some combination of pap, hly, or cnf-1and therefore most likely to represent pathogenic strains (19); group 3, 20 unique first-time UTI isolates (40); group 4, 15 unique recurrent UTI isolates (40); group 5, 21 blood isolates obtained from patients hospitalized at Erie County Medical Center; group 6, all 35 UTI isolates (groups 3 and 4); group 7, all 56 clinical isolates (groups 3 to 5).

  • b 0, no homology; 1+, positive homology; 2+, maximal homology; any+, combination of 1+ and 2+.

  • c Fisher’s exact test was used for proportions. All comparisons are versus group 1.

  • d P = 0.039.

  • e P = 0.004.

  • f P = 0.003.

  • g P > 0.10 (not significant).

  • h P = 0.01.

  • i P = 0.03.