Table 2.

Change in capsular polysaccharide-specific antibody after pneumococcal vaccination of elderly

SerotypeaGMC antibody increase (μg/ml)% with >1 μg/ml increase in concnMean fold rise% with >2-fold rise
1411.0777.82.3651.9
43.1866.72.1744.4
23F6.3775.92.6053.7
15.7483.32.5046.3
31.0050.01.4431.5
22F3.7966.72.8051.9
6B6.1875.92.8353.7
83.5270.43.2863.0
19A7.1875.92.8255.6
12F3.2264.82.3853.7
19F8.8285.22.5763.0
7F10.6883.34.0963.0
18C9.3488.93.3963.0
9V8.2079.63.3064.8
33F15.9090.76.5777.8
9N11.8387.03.8366.7
59.8383.33.3563.0
11A4.7581.52.1344.4
2013.7388.93.3364.8
15B14.8888.94.0875.9
10A9.5479.63.2155.6
17F4.4868.52.4151.9
27.7483.34.2772.2
  • a In order of decreasing prevalence of vaccine serotypes among 791 invasive S. pneumoniae isolates from adults over 35 years old in Minnesota from 1995 to 1998 (17).