Table 1.

Prevaccination antibody levels for capsular PPSs in elderly subjects

SerotypeaGMC of antibody (μg/ml)95% confidence interval% of elderly with <1 μg/ml concn
148.126.58–10.030
42.721.99–3.7318.5
23F3.983.13–5.067.4
13.822.73–5.3411.1
32.261.95–2.617.4
22F2.111.59–2.7933.3
6B3.382.57–4.4411.1
81.541.19–2.0027.8
19A3.962.97–5.275.6
12F2.341.68–3.2418.5
19F5.614.32–7.295.6
7F3.462.60–4.6111.1
18C3.902.98–5.119.3
9V3.572.66–4.7911.1
33F2.852.02–4.0431.5
9N4.183.20–5.457.4
54.193.20–5.477.4
11A4.183.30–5.315.6
205.894.42–7.865.6
15B4.833.75–6.225.6
10A4.323.08–6.055.6
17F3.172.38–4.2316.7
22.371.79–3.1318.5
  • a In order of decreasing prevalence of vaccine serotypes among 791 invasive S. pneumoniae isolates from adults over 35 years old in Minnesota from 1995 to 1998 (17).