Infection rate or parameter | PBS (sham) | Pn 14 | n (both groups) |
---|---|---|---|

Infection rate | 73.9% | 25.0% | 24 |

Serum α Pn 14 IgG (days 28 and 33)^{a} | 0.0 ± 0.0 | 0.0 ± 0.0 | 18 |

Serum α CPS IgG (day 28)^{a} | −0.03 ± 0.03 | 0.31 ± 0.10^{d} | 18 |

Serum α CPS IgG (day 33)^{a} | −0.02 ± 0.07 | 0.58 ± 0.17^{d} | 18 |

IgA plasma cells/mm^{2} of mucosa^{b} | 5.3 ± 0.2 | 12.9 ± 1.4^{d} | 3 |

↵a Days 28 and 33 represent the change in value at the time of challenge and of section, respectively. IgG serum titers are the means of differences ± standard errors of the mean between the values before (day 0) and after priming (days 28 and 33); nonresponders are included. IgG titers are presented as log

_{10}dilution at 50% maximum optical density.↵b For IgA immunochemistry, bullae from three randomly chosen animals from each group were prepared on day 6 after challenge.

c Significantly different (P < 0.05) from values in sham-treated groups as calculated by a Fisher's exact test.

↵d Significantly different (P < 0.05) from values in sham-treated groups as calculated by a Student's t test.