Table 1.

Opa protein phenotypes of vaginal isolates from estradiol-treated BALB/c and SLC:ddY mice following inoculation with a predominantly Opa-negative population of FA1090a

Strain and mouse no.bOpa protein phenotype (%) on day:
1458
BALB/c
 2Negative (79), I (13), E/K (4), B (4)Negative (44), I (44), B (4), A (4), D,I (4)Negative (55), I (20), F (10), B (5), A,I (5), A (5)
 6Negative (71), I (29)I (100)I (95), E/K,I (5), negative (5)
 7Negative (42), F (33), D (17), B (8)Negative (67), B (13), I (13), D (4), F (4)B (67), negative (25), B,F (8)
SLC:ddY
 62Negative (71), B (25), I (4)I (46), negative (42), B (8), A (4)
 9Negative (50), B,I (20), E/K (13), B,E/K (6), B (6), F (6)Negative (55), I (20), C (10), C,I (10), B (5)B,C (33), B (21), B,I (17), I (8), C,I (8), F,I (4), negative (4), B,C,E/K (4)
 17Negative (88), B (6), F (6)Negative (58), I (18), B (8), C (8), F (8)
  • a The inocula were 94% Opa negative, 3% OpaB, and 3% OpaA (BALB/c mice); 92% Opa negative, 4% OpaB, and 4% OpaA (SLC:ddY mouse 62); and 97% Opa negative and 3% OpaB (SLC:ddY mice 9 and 17). Other Opa variants were undoubtedly present in the inoculum suspensions but were below the limits of detection.

  • b The BALB/c mice were from the experiment depicted in Fig. 4A, and the SLC:ddY mice were from the two experiments depicted in Fig. 4B.