Table 2.

Protective effect of immunization with a combination of OmpL1-M and LipL41-M

GroupNo. (%) of surviving animals/groupa
Expt 1Expt 2Expt 3Total
OmpL1-M9/9 (100)0/6 (0)1/9 (11)10/24 (42)
Control3/9 (33)0/6 (0)3/15 (20)
 SignificanceP < 0.004NSNSb NS
LipL41-M2/7 (29)1/6 (17)2/9 (22)5/22 (23)
Control3/9 (33)0/6 (0)3/15 (20)
 SignificanceNSNSNSb NS
OmpL1-M + LipL41-M9/9 (100)3/6 (50)5/9 (55)17/24 (71)
Control3/9 (33)1/6 (17)2/9 (22)6/24 (25)
 SignificanceP < 0.004NSNS P < 0.001
  • a Number of surviving animals at 28 days after challenge/number of animals challenged. Statistical analysis was performed by using Student's t test for two independent means (significance, P < 0.05). NS, not significant.

  • b Significance determined by comparison to control group for OmpL1-M + LipL41-M arm of experiment 3.