TABLE 2

Virulence of the ΔyopK mutant in BALB/c mice determined via i.v. and s.c. challenges

Y. pestis strainLD50 (CFU) after challenge:
i.v.s.c.
FirstSecond
20194316
201 ΔyopK1,7781,38010
201 ΔyopK-CyopK73898.9