Table 4.

Categorization of United Kingdom MCC toddler sera post-primary MCC rSBA titers into numbers positive by fourfold rises, response to boosting, and avidity maturation

Post-MCC rSBA titer Vaccine No. with fourfold rise in titer from pre- to post-MCC/ total no. (%)No. with rSBA titer of ≥128 post-10-μg MACP booster/ total no. (%) No. with avidity maturationa/ total no. (%)
<8 All 0/11 (0)8/9 (89) 3/5 (60)
8–64 All 48/49 (98)39/43 (91) 25/27 (93)
≥128 All 116/117 (99)137/141 (97) 78/86 (91)
  • a Rise in avidity from post-MCC to pre-MACP booster.