Table 1.

Adoptive transfer of UreA-specific CD4+ T cells to naive mice reduces gastric colonization by H. pylori as early as 7 days after infection

Daysb after infectionNo. of CFUa recovered from the stomachs of:
Infected mice SL3261[pYZ97]-vaccinated, challenged mice Challenged mice receiving UreA- specific CD4+ T cells Challenged mice receiving ovalbumin-specific CD4+ T cells
75.28 ± 0.27 4.23 ± 0.474.68 ± 0.26 Not done
215.53 ± 0.18 4.52 ± 0.39 5.01 ± 0.28Not done
425.50 ± 0.59c 3.85 ± 0.91c 5.00 ± 0.81c 5.77 ± 0.31d
  • a Values are expressed as log10 CFU/gram tissue ± standard deviation.

  • b Values for days 7 and 21 are from one experiment (five to seven mice per group).

  • c Values are the average of three experiments (20 mice in all).

  • d This experiment was done once.