Table 3.

Correlations between the structure of thecag PAI and IL-8 induction ability

Structure of cag PAINo. of IL-8 inducers/ total no. of strains (%)Avg (SD) IL-8 production (pg/ml)
Uninterrupted60/78 (76.9)454.1 (751.7)
No cag PAI8/40 (20)102 (280.5)
cag PAI split in two8/12 (66.6)632.9 (864.5)
Other combinations4/8 (55.5)a
  • a One strain had the middle region and cagII (IL-8 production, 10.8 pg/ml), two strains had the middle region and cagI, (137.8 pg/ml), one strain had cagII only (113.3 pg/ml), one strain had cagI only (25.2 pg/ml), one strain had the middle region only (250 pg/ml), and three strains had cagA only (70.45 pg/ml).