Table 2.

rSBA titers 4 weeks after vaccination with MCC vaccine (10-μg dose)a

Vaccine manufacturer and age at first dose No. of doses No. tested GMTbNo. (%) of subjects with indicated postvaccination rSBA titer:
≤4 8–64 ≥128
Wyeth
 2 mo1 50 3316 (32) 15 (30) 19 (38)
 2 mo 2 (1 mo apart) 56 776 1 (2) 3 (5)51 (93)
 2 mo 3 (1 mo apart) 53 1,011 1 (2)1 (2) 51 (96)
 12–14 mo 1 71 141 6 (8)17 (24) 48 (68)
 3–4 yr 1 87 908 1 (1)10 (11) 76 (88)
 14–17 yr 1 81 3,8900 (0) 0 (0) 81 (100)
 18–26 yr 1 861,425 0 (0) 6 (7) 80 (93)
Chiron
 12–14 mo 1 72 123 6 (8)29 (40) 37 (52)
NAVA
 12–14 mo 1 72 564 0 (0)7 (10) 65 (90)
  • a Data from United Kingdom trials.

  • b GMT, geometric mean titer.