Table 2.

Infectious contenta of R. australis in IFN-γ gene knockout mice subjected to adoptive transfer with immune or nonimmune CD8 T lymphocytes

Group no.Adoptive transfer103 PFU of R. australis/g of tissue from the:
SpleenLungsLiver
1Immune CD8b29.6 ± 1.517.2 ± 3.919 ± 0.9
2Naı̈ve CD84,814 ± 7585,449 ± 2822,837 ± 400
3No transfer2,816 ± 1892,778 ± 3791,996 ± 163
  • a Mean of two repeated experiments, ± standard deviation.

  • b Immune IFN-γ gene knockout CD8 T-lymphocyte recipients' organs contained significantly fewer R. australis PFU than the corresponding organs of recipients of naı̈ve IFN-γ gene knockout CD8 T lymphocytes (P < 0.05) or those of mice with no transfer (P < 0.05) .