Table 2.

Cytotoxicity of Salmonella serovar Typhimurium grown to logarithmic or stationary phase and a sipB mutant for macrophages from cattle naturally resistant or susceptible toB. abortus at 1 and 6 h after infection

Strain% Macrophage survival at the following hour postinfection for the indicated cattlea:
16
ResistantSusceptibleResistantSusceptible
Logarithmic phase81.17 ± 6.7488.71 ± 37.9261.35 ± 12.3865.01 ± 33.32
Stationary phase130.61 ± 8.14134.79 ± 42.31132.44 ± 7.37140.92 ± 37.95
sipBmutant125.56 ± 10.67132.22 ± 46.05153.09 ± 2.06153.46 ± 50.49
  • a Values are means and standard deviations for the percentage of macrophage survival in comparison to that in the uninfected control (see Materials and Methods). The experiments were performed in quadruplicate with three animals in each group. There was no significant difference between resistant and susceptible cattle (P > 0.05).