Table 2.

MLST of 212 GAS isolatesa

StrainemmtypecodebSTAssigned no. for alleleSourceYearOrigin
gkigtrmurImutSrecPxptyqiL
86-7791m1-1284344424URTa1986Ohio
87-2141m1-2284344424URT1987Chile
CT95-1111m1-3284344424Invasive1995Connecticut
CT95-1201m1-4284344424Invasive1995Connecticut
CT95-1311m1-5284344424Invasive1995Connecticut
CT95-1321m1-6284344424Invasive1995Connecticut
CT95-1801m1-7284344424Invasive1995Connecticut
CT983601m1-8284344424Invasive1998Connecticut
CT984191m1-9284344424Invasive1998Connecticut
CT985201m1-10284344424Invasive1998Connecticut
700294-ATCC1m1-11284344424InvasiveNDdND
MGAS1661m1-12284344424InvasiveNDMinnesota
MGAS21271m1-13284344424NDNDIndia
MGAS2831m1-14284344424InvasiveNDColorado
MGAS3021m1-15284344424InvasiveNDWashington
MGAS3071m1-16284344424InvasiveNDTexas
MGAS21101m1-17912621853131NDNDNew Zealand
MGAS21201m1-18922725443221ImpetigoNDAustralia
MGAS21251m1-19922725443221ImpetigoNDAustralia
MGAS21091m1-2093282544421URTNDNew Zealand
MGAS21441m1-2193282544421URTNDNew Zealand
MGAS22261m1-2293282544421URTNDNew Zealand
MGAS21231m1-23942825444201ImpetigoNDAustralia
B3442m2-15511919234URT1950Massachusetts
D7252m2-25511919234URT1973New York
89-4652m2-35511919234URT1989Nebraska
CT95-1972m2-45511919234Invasive1995Connecticut
CT985492m2-55511919234Invasive1998Connecticut
MGAS2862m2-65511919234InvasiveNDColorado
MGAS3272m2-75511919234InvasiveNDArizona
C1993m3-1152685232URT1942New York
1GL903m3-2152685232URT1946Illinois
2GL2153m3-3152685232URT1946Illinois
1RP2283m3-4152685232URT1959New York
D4253m3-5152685232Invasive1971New York
CT95-1173m3-6152685232Invasive1995Connecticut
CT95-1193m3-7152685232Invasive1995Connecticut
CT95-1333m3-8152685232Invasive1995Connecticut
CT95-1453m3-9152685232Invasive1995Connecticut
CT95-1863m3-10152685232Invasive1995Connecticut
CT95-2043m3-11152685232Invasive1995Connecticut
CT984293m3-12152685232Invasive1998Connecticut
MGAS1573m3-13152685232InvasiveNDMinnesota
MGAS1593m3-14152685232InvasiveNDUtah
MGAS2683m3-15152685232InvasiveNDMinnesota
MGAS2773m3-16152685232InvasiveNDColorado
88-0193m3-171626816232URT1988North Carolina
CT95-2003m3-181822785232Invasive1995Connecticut
2RP1134m4-13857851521Invasive1952New York
1RP1564m4-23857851521URT1954New York
A8374m4-33857851521Invasive1965Unknown
87-2314m4-439511851521URT1987Ohio
CT95-1954m4-539511851521Invasive1995Connecticut
YL054m4-639511851521Invasive1997Connecticut
CT986934m4-739511851521Invasive1998Connecticut
YL084m4-839511851521Invasive1999Connecticut
09C024m4-939511851521InvasiveNDND
MGAS3204m4-1039511852921InvasiveNDTexas
CT985294m4-1140511852924Invasive1998Connecticut
1RP1445m5-1993330755263URT1953New York
87-2925m5-2993330755263URT1987Ohio
CT95-1185m5-3993330755263Invasive1995Connecticut
CT983025m5-4993330755263Invasive1998Connecticut
Manfredo5m5-5993330755263URT1958Illinois
MGAS2545m5-6993330755263InvasiveNDCalifornia
MGAS2585m5-7993330755263InvasiveNDCalifornia
1RP1126m6-1375255543URT1952New York
D4716m6-2375255543ND1971Egypt
87-2856m6-3375255543URT1987Utah
87-3766m6-4375255543URT1987Colorado
CT95-1156m6-5375255543Invasive1995Connecticut
MGAS2916m6-6375255543InvasiveNDColorado
297408m859132819134Impetigo1988Czech Republic
D7339m9-1731514771931ND1973Unknown
1RP2789m9-27415147161931URT1964New York
MGAS2809m9-37515147181931InvasiveNDColorado
CT95-12611m11-1203465151Invasive1995Connecticut
CT95-15511m11-2203465151Invasive1995Connecticut
CT9830311m11-3203465151Invasive1998Connecticut
CT9841411m11-4203465151Invasive1998Connecticut
CT9853811m11-5213465152Invasive1998Connecticut
ALAB7911m11-6223467154Impetigo1986Alabama
D69111m11-72334671154URT1972Trinidad
2RP19612m12-1365226622URT1956New York
A37412m12-2365226622URT1960Trinidad
CT95-12712m12-3365226622Invasive1995Connecticut
CT9838612m12-4365226622Invasive1998Connecticut
CT9864712m12-5365226622Invasive1998Connecticut
MGAS27812m12-6365226622InvasiveNDColorado
CT95-12213m13-18924235131Invasive1995Connecticut
MGAS24813m13-28924235131InvasiveNDCalifornia
25RS8414m1485202223271814URT1942New York
1GL21717m1783192111533URT1946Illinois
88-09218m18-1416571533URT1988Pennsylvania
1RP6218m18-2426571563URT1949New York
4RP10418m18-3426571563URT1951New York
1RP26818m18-4426571563URT1963New York
A94118m18-5426571563URT1967New York
87-28218m18-6426571563URT1987Ohio
87-37318m18-7426571563URT1987Utah
MGAS30018m18-8426571563InvasiveNDWashington
1RP11819m19-165137811398URT1952New York
1RP23219m19-265137811398URT1959New York
1GL20519m19-3691378101398URT1946Illinois
D70919m19-4691378101398URT1973New York
B24322m22-1459811133ND1947United Kingdom
MGAS27522m22-2469811134InvasiveNDColorado
MGAS33022m22-3469811134InvasiveNDND
MGAS33922m22-4469811134InvasiveNDTexas
22RS7224m24-1661378113128URT1941New York
1RP28424m24-2701318811398URT1964New York
D31625m25541171571734Invasive1969New York
11RS10026m26671378126313URT1942New York
CT95-18928m28-15211614591719Invasive1995Connecticut
CT9822028m28-25211614591719Invasive1998Connecticut
CT9860128m28-35211614591719Invasive1998Connecticut
MGAS25528m28-45211614591719InvasiveNDCalifornia
MGAS32528m28-55211614591719InvasiveNDND
3RP7029m29-165137811398URT1949New York
D47029m29-265137811398ND1971Egypt
10RS10132m3211111111URT1942New York
13RS6033m33-132212222URT1941New York
A98233m33-232212222Impetigo1968New York
6010-533m33-332212222Impetigo1971Alabama
2948733m33-432212222Impetigo1987Czech Republic
MGAS30633m33-532212222InvasiveNDND
C14234m3464137819223ND1942Unknown
A45736m364791612025316ND1961Yugoslavia
19RS1439m3932417251251Invasive1941New York
1RS7942m428016151971217Invasive1941New York
D40743m4342212232Invasive1971New York
C13549m49-1294627775URT1942New York
A94549m49-2294627775Impetigo1966Minnesota
B73749m49-33046272171Impetigo1957Minnesota
MGAS16349m49-43442927774InvasiveNDLouisiana
A20350/62m502122053534Mouse1959New York
MGAS32350/62m62-12122053534InvasiveNDIdaho
MGAS32450/62m62-22122053534InvasiveNDIdaho
A29151m5184202223271812ND1960Delaware
A94652m52437283822Impetigo1971Trinidad
D94853m53-1112612222Impetigo1976Trinidad
ALAB4953m53-2112612222Impetigo1986Alabama
AP5353m53-3112612222ImpetigoNDMinnesota
D48855m5510034222112916Impetigo1971Trinidad
D30657m57334262371283ND1968Trinidad
2945458m58193233333Impetigo1987Czech Republic
4500-S60m60531162279217Impetigo1960Alabama
A95663m6388232423231918ND1967Unknown
ALAB5366m66-1448788931Impetigo1986Alabama
MGAS16766m66-2448788931InvasiveNDTexas
D79567m7661132161531ND1975Georgia
5552-S68m68862131132834Impetigo1971Alabama
D99870m7024342454236ND1976Japan
CT95-12173m73722931834Invasive1995Connecticut
86-80975m75-149112131237URT1986Utah
CT95-15475m75-249112131237Invasive1995Connecticut
CT95-17175m75-349112131237Invasive1995Connecticut
MGAS26475m75-449112131237InvasiveNDCalifornia
CT9820076m76-150116366274Invasive1998Connecticut
CS11076m76-251116126624NDNDUnknown
MGAS26177m77-13543121334321InvasiveNDCalifornia
CT95-15977m77-2631362323311Invasive1995Connecticut
CT9859477m77-3631362323311Invasive1998Connecticut
MGAS33177m77-4631362323311InvasiveNDNew York
D81278m78-17616283131Impetigo1975Trinidad
CT95-15778m78-2791621131111Invasive1995Connecticut
CT95-10480m808229318112Invasive1995Connecticut
2966581m81571123272432Impetigo1988Czech Republic
2RSC338/40m38/40811719111153URT1942New York
3RP14144/61m44/61-125423111731URT1953New York
D93844/61m44/61-225423111731Impetigo1976Trinidad
1RP18RN44/61m44/61-3314103614104URT1946New York
5569-S44/61m44/61-4314103614104Impetigo1971Alabama
MGAS29682 (pt180)m82264221161731InvasiveNDWashington
ALAB5583 (pt2110)m83-152223232Impetigo1986Alabama
2968983 (pt2110)m83-252223232Impetigo1988Czech Republic
D94384 (pt2233)m84-158122131287Impetigo1976Trinidad
MGAS1914A84 (pt2233)m84-258122131287NDNDND
D96486 (pt2631)m869229318142Impetigo1976Trinidad
10RS5787 (pt2841)m876213310122023URT1941New York
D97688 (pt3875)m8890252136302515ND1976Trinidad
MGAS201789 (pt4245)m89-177162831111URT1991United States
MGAS201889 (pt4245)m89-277162831111URT1992United States
CT95-17689 (pt4245)m89-377162831111Invasive1995Connecticut
CT9867789 (pt4245)m89-477162831111Invasive1998Connecticut
D42489 (pt4245)m89-578162871131Invasive1971New York
89-45690 (pt4931)m905611925254URT1989Kuwait
C50691 (pt5757)m91-1122615222URT1943Unknown
D82191 (pt5757)m91-21326252232Impetigo1975Trinidad
4426-S92 (st2974)m92-1821820792215Impetigo1970Alabama
MGAS27092 (st2974)m92-2821820792215InvasiveNDMinnesota
D46693 (potter41)m93-110229132142ND1971Egypt
D50293 (potter41)m93-217213852310Impetigo1971Trinidad
2GL32st1RP31strp31-165137811398URT1946Illinois
1RP31st1RP31strp31-268137812698URT1947New York
CT95-169st2346st2346-160132141931Invasive1995Connecticut
MGAS319st2346st2346-260132141931InvasiveNDIdaho
29486st2370.1st2370.16228321612Impetigo1987Czech Republic
MGAS341st3365st33659731225352412InvasiveNDMissouri
MGAS308st4529st4529721428217451InvasiveNDWashington, D.C.
6250-Sst4935st49352743252261Impetigo1972Alabama
D997st4973st497398326832822ND1976Japan
MGAS273st64/14m64/14-1142683931InvasiveNDCalifornia
MGAS2111st64/14m64/14-2142683931NDNDND
MGAS2140st833st8339529322533214NDNDND
A756stA207stA207-1872210171414320Invasive1964New York
MGAS288stA207stA207-2872210171414320InvasiveNDColorado
D432stD432stD432711412271659ND1971Egypt
D626estD626stD6269229318142Impetigo1972Trinidad
D631stD631stD6319630291318142Impetigo1972Trinidad
D633stD633stD63348106261036Impetigo1972Trinidad
D641stNS5stNS5112612222Impetigo1972Trinidad
  • a Note: emm13 is equivalent toemm13W, emm77 is equivalent to emm27L, andemm50 is equivalent to emm62(http://www.cdc.gov/ncidod/biotech/strep/strains.html ).

  • b Codes for strains were used in dendrogram (Fig. 1).

  • c URT, upper respiratory tract.

  • d ND, not determined.

  • e Strain D626 was previously assigned asemmst88/31 (6) but is now correctly considered to be a new type (emmstD626; GenBank accession no.AF338251 ).