Table 1.

Opsonophagocytic activity with healthy control adult serum (HC1) and MAb B5 (10× concentrated culture supernatant) and PMNms with different phenotypes of N. meningitidis MC58

N. meningitidis strainPhenotypeMean % opsonophagocytic activity
CapsuleOpaOpcPilinLPSControlaFinal bufferbHC1MAb B5MAb B5c
MC58 Cap+ ++++L39.45.873.952.142.7
MC58 Cap +++L314.710.980.963.348.7
c3++L310.49.545.846.035.7
c5+L37.15.651.048.3541.2
c10+L317.97.869.658.9541.0
c12L35.96.162.951.845.9
  • a Complement only.

  • b Final buffer control only.

  • c Complement background control value subtracted.