Table 1.

Epidemiological properties and MLST analysis of GCS and GGS

StrainTissueaDiseaseaYrLocationbemm typeGroup carbohydrateSTAllele assignmentscCode in dendrogram
gkigtrmurImutSrecPxptyqiL
4236SterileInvasiveNDUSAstG643G1 101106104101116101107GstG643
4031BloodBacteremia1998ArgentinastG4831G2 102102103106104114106GstG4831
4949URTNone1996IndiastC839C3 103104109106103107105Cst839-1
4241SterileInvasiveNDUSAstC839C4 103104112106101107112Cst839-2
4231SterileInvasiveNDUSAstG653C5 103105111106101107116CstG653
5341URTND1920sUKstG93464C6 103111109106101107110Cst93464
SS1069URTND1974N.J.stC839C7 103111109106101107112Cst839-3
MGAS338SterileInvasive1980sUSAstC839C8 104102109106101107104Cst839-4
4966URTPharyngitis1996IndiastC839C9 104111109106101107107Cst839-5
4277SterileInvasiveNDUSAstC36G10105106109103104111109GstC36
5344SkinWound1980sUKstC5344C11105106112106113105111CstC5344
4232SterileInvasiveNDUSAstG10G12105109109106113104113GstG10-1
1891SterileCellulitis1999Ill.stG480G13106101101106113104102Gst480-1
D421SkinImpetigo1971TrinidadstG480G14106103102106113104103Gst480-2
4030BloodBacteremia1998ArgentinastG11G15106104105106113104106GstG11-1
4234SterileInvasiveNDUSAstG480G16106108105104113104111Gst480-3
4255SterileInvasiveNDUSAstG653G17106108105106114104107GstG653
5353SkinUlcer1980sUKstG11G18106110109106113104113GstG11-2
5357SkinUlcer1980sUKstG652G19107112108105111109108GstG652
1778URTND1993Wyo.stC36C20108106105102102102110CstC36-1
4288SterileInvasiveNDUSAstG485C21108106105106107104114Cst485
4265SterileInvasiveNDUSAstC36C22108106106106108106108CstC36-2
4242SterileInvasiveNDUSAstG485G23108107109105102104115Gst485-1
4276SterileInvasiveNDUSAstG10G24108109107105105110116GstG10-2
3296NDUnknown1994Ariz.stG485G25108109109105102104116Gst485-2
5354BloodBacteremia1980sUKstG62467G26108109109106107113113Gst62467
SS957NDND1969NDstC957C27108111105106109104109CstSS957
SS188URTND1941USAstC74aC28108113109106108112111CstC74a
4286SterileInvasiveNDUSAstG6G29108113109106110115109GstG6
1775URTND1993Wyo.stC36C30108114110102107101108CstC36-3
5345BloodBacteremia1983UKstG5345C31108115109105112108110CstG5345
3110BloodInvasive1994Ariz.stG643C32108116109105115103115CstG643
4247SterileInvasiveNDUSAstC74aG33109109109105102104110GstC74a
4951URTARF1996IndiastG4974G34110101109106106115101GstG4974
  • a Isolation of a GCS or GGS organism from a subject with noninvasive disease does not necessarily imply that the organism caused that disease. Sterile, a normally sterile site; URT, upper respiratory tract; ARF, acute rheumatic fever. ND, not determined.

  • b UK, United Kingdom.

  • c Allele assignments in bold are assigned to cluster II, whereas the allele in bold italics (recP116) is highly divergent from both sequence similarity clusters I and II (see Table 3 and Fig. 2).