Table 2.

Effect of challenge infection with B. abortus2308 on spleen weight of vaccinated and unvaccinated micea

TreatmentSpleen weight (mg)b
3 days6 days10 days
None + challenge136 ± 13 254 ± 34∗∗ 258 ± 68∗∗
Vaccination + challenge158 ± 23 180 ± 42 132 ± 22
  • a BALB/c mice were treated as shown, and spleen weights were assessed at 3, 6, and 10 days after challenge infection. Data are mean values of five animals ± SD.

  • b Group with different number of asterisks are significantly different (P ≤ 0.05) .