Table 1.

Effect of vaccination with B. abortus RB51 on spleen weighta

TreatmentSpleen weight (mg)b
6 days18 days42 days
None100 ± 10 96 ± 5 95 ± 7
Vaccination168 ± 31∗∗ 358 ± 53∗∗ 180 ± 6∗∗
  • a BALB/c mice were treated as shown, and spleen weights were assessed at 6, 18, and 42 days after vaccination. Data are mean values of five animals ± SD.

  • b Groups with a different number of asterisks are significantly different (P ≤ 0.05) .