Table 3.

Persistence of B. abortus 2308 in spleens of vaccinated and unvaccinated micea

TreatmentCFU of B. abortus 2308 cells in spleenb
3 days6 days10 days
None + challenge9.3 × 104 ± 6.7 × 104 ∗∗ 2 × 106 ± 1 × 106 ∗∗ 4.7 × 106 ± 1 × 106 ∗∗
Vaccination + challenge7.3 × 103 ± 5.4 × 103 1.2 × 104 ± 2.1 × 104 1.9 × 104 ± 2.2 × 104
  • a BALB/c mice were treated as shown, and bacteria present in spleen were assessed at 3, 6, and 10 days after vaccination. Data are mean values of five animals ± SD.

  • b Group with different number of asterisks are significantly different (P ≤ 0.05) .