TABLE 1

mod alleles and repeat numbers for K. kingae isolate strainse

StrainmodK allelecClinical syndrome/isolationAGCC repeat tract no.b (ON/OFF)Sequence sourceCountry of isolation
ATCC 23330amodK1Carrier isolate11 (OFF)HMPREF0476_1726-HMPREF0476_1725, reference genome, GL891963.1Norway
KK789modK1Blood culture8 (OFF)This studyMDU, Australia
KK791modK1Lesion chest wall, chest tissue15 (OFF)This studyMDU, Australia
KK002modK1Corneal scraping13 (ON)This studyRoyal Brisbane Hospital, Australia
KK003modK1Synovial fluid13 (ON)This studyRoyal Brisbane Hospital, Australia
KK247amodK2Endocarditis19 (ON)CCJT01000004Israel
KK781modK2Joint fluid7 (ON)This studyMDU, Australia
KK782modK2Ankle fluid14 (OFF)This studyMDU, Australia
KK792modK2Fever, swollen joints, blood culture11 (OFF)This studyMDU, Australia
KK793modK2Swelling, redness, rash right heel, blood10 (ON)This studyMDU, Australia
KK794modK2Blood5 (OFF)This studyMDU, Australia
KK190modK2EndocarditisNDPRJEB1631Israel
KK128modK2EndocarditisNDPRJEB1630Israel
PYKK081amodK3dSeptic arthritis26 (OFF)KKB_09104-KKB_09099-KKB_09094 (27), AJGB01000058.1Israel
KK783modK3dFever, rigors, blood culture3 (OFF)This studyMDU, Australia
KK784modK3dFebrile, nausea, vomiting, diarrhea, blood culture2 (OFF)This studyMDU, Australia
KK790modK3dSeptic left hip, left hip fluid3/4 mixed (OFF/ON)This studyMDU, Australia
KK795modK3dVomiting and diarrhea, blood3 (OFF)This studyMDU, Australia
KK001modK3dFluid left knee25 (ON)This studyRoyal Brisbane Hospital, Australia
KK004modK3dSynovial left knee28 (ON)This studyRoyal Brisbane Hospital, Australia
11220434amodK4dHealthy carrierNDALIJ01000087Israel
KK83modK4dOsteoarticular infectionNDPRJEB1616Israel
KK12modK4dHealthy carrierNDPRJEB1638Israel
KK6modK4dHealthy carrierNDPRJEB1643Israel
KK199modK4dEndocarditisNDPRJEB1628Israel
KK156modK4dArthritisNDPRJEB1618Israel
KK260modK4dBacteremiaNDPRJEB4190Israel
Kk274modK4dArthritisNDPRJEB1619Israel
KK411modK4dEndocarditisNDPRJEB1629Israel
KK101modK4dOsteomyelitisNDPRJEB1613Israel
AA417modK4dHealthy carrierNDPRJEB1646Israel
KK107modK4dHealthy carrierNDPRJEB1645Israel
KK145modK4dArthritisNDPRJEB1617Israel
Vir5453modK4dHealthy carrierNDPRJEB1637Israel
BB114modK4dHealthy carrierNDPRJEB1632Israel
AA068modK4dHealthy carrierNDPRJEB1647Israel
KK189modK4dBacteremiaNDPRJEB4188Israel
KK75modK4dArthritisNDPRJEB1626Israel
KK141modK4dOsteomyelitisNDPRJEB1621Israel
KK245modK4dBacteremiaNDPRJEB4192Israel
KK158modK4dBacteremiaNDPRJEB4189Israel
BB631modK4dHealthy carrierNDPRJEB1654Israel
D7330modK4dHealthy carrierNDPRJEB1633Israel
KK3modK4dHealthy carrierNDPRJEB1636Israel
PV1748modK4dHealthy carrierNDPRJEB1652Israel
KK113modK4dHealthy carrierNDPRJEB1634Israel
CC254modK4dHealthy carrierNDPRJEB1653Israel
KK171modK4dArthritisNDPRJEB1625Israel
AA105modK4dHealthy carrierNDPRJEB1639Israel
BB016modK4dHealthy carrierNDPRJEB1648Israel
AA255modK4dHealthy carrierNDPRJEB1640Israel
KK97modK4dBacteremiaNDPRJEB4187Israel
KK98modK4dBacteremiaNDPRJEB4191Israel
BB060modK4dHealthy carrierNDPRJEB1635Israel
KK88modK4dOsteomyelitisNDPRJEB1614Israel
KK93modK4dBacteremiaNDPRJEB4186Israel
D2363modK4dHealthy carrierNDPRJEB1649Israel
KK60modK4dEndocarditisNDPRJEB1627Israel
KK238modK4dOsteomyelitisNDPRJEB4185USA
KK242modK4dArthritisNDPRJEB1624Israel
KK56modK4dArthritisNDPRJEB1623Israel
KK785modK4dBlood16 (ON)This studyMDU, Australia
KK788modK4dLeft tibia abscess, abscess aspirate12 (OFF)This studyMDU, Australia
KK796modK4dFebrile, oncology blood15 (OFF)This studyMDU, Australia
  • a Genome strains.

  • b Number and expression state of repeats within the modK gene. ON, in frame for expression; OFF, out of frame for expression. ND, not able to be determined from draft genomes.

  • c A strain was defined as having the modK1, modK2, modK3, or modK4 allele if the DNA recognition region was ≥95% identical at the nucleotide level to modK1 of K. kingae strain ATCC 23330, modK2 of strain KK247, modK3 of strain PYKK081, or modK4 of K. kingae strain 11220434 (Fig. 1).

  • d modK3 and modK4 strains that contain a premature stop codon.

  • e Refer to Fig. 1 and to the text.