Table 1.

Entry of B. cepacia J2315 and J2540 into cultured U937 macrophages and A549 respiratory epithelial cellsa

StrainU937 MacrophagesA549 Epithelial cells
% Invasion (MOI 10:1)% Invasion (MOI 70:1)% Invasion (MOI 10:1)% Invasion (MOI 100:1)
J23155.82 ± 0.2253.30 ± 0.190.15 ± 0.00630.10 ± 0.0019
J25405.49 ± 0.0563.16 ± 0.350.024 ± 0.00150.034 ± 0.0017
E. coliHB1010.0028 ± 0.00050.011 ± 0.000020.0058 ± 0.0000350.0082 ± 0.0005
  • a Invasion assays were performed as described in Materials and Methods. Values represent the percentage of the bacterial inoculum that survived 2 h antibiotic treatment and are the means ± the standard deviation of six independent determinations with a total of three wells.