Table 1.

G. lamblia infections in immunodeficient mice

ExptMiceDay 7Day 14Day 28
InfectedaIntensitybInfectedIntensityInfectedIntensity
1C57BL/6J3/37.1 ± 4.41/30.3 ± 0.60/3 NDg
B6 Igh-63/322.1 ± 6.3c,d 1/30.3 ± 0.6d 0/3ND
B6 SCID3/3164.2 ± 62.1c 3/3197.1 ± 100.3c 3/3e 150.8 ± 15.8
B6 TCRβ3/345.0 ± 8.2c,d 3/351.7 ± 12.1c,d 3/3e 53.8 ± 17.7d
2C57BL/6J3/313.3 ± 11.12/31.3 ± 1.21/30.3 ± 0.6
B6 SCID3/379.2 ± 37.4c 3/3185.0 ± 73.7c 3/3140.0 ± 47.7c
B6 TCRβ3/3185.0 ± 50.7c,d 3/391.7 ± 36.2c,d,f 3/350.0 ± 10.0c,d,f
  • a The number of mice with detectable parasites in the gut/total number of mice analyzed on the day indicated postinfection.

  • b The average ± standard deviation of the number of parasites/mouse × 104.

  • c P < 0.01 versus the value for C57BL/6J mice.

  • d P < 0.01 versus the value for B6 SCID mice.

  • e P < 0.08 versus the value for C57BL/6J mice.

  • f P < 0.01 versus the value on day 7.

  • g ND, none detected.