Table 1.

Serum and salivary antibody responses to PspA, PsaA, and PdBa

AntibodyNo. of micebImmunogens
SourceSpecificityCTB onlyrPspA + CTBrPsaA + CTBrPdB + CTBrPspA + rPsaA + CTBrPspA + rPdB + CTBc
SerumPspA12<0.00230.9 (1.4)<0.002<0.00232.4 (1.2)10.5 (1.2)
SerumPsaA12<0.034<0.034257 (1.15)<0.034234 (1.2)<0.034
SerumPdB8<0.0009<0.0009<0.00092.15 (1.1)<0.00092.45 (1.3)
SalivaPspA12<0.0020.014 (1.8)<0.002<0.0010.008 (1.2)NDd
SalivaPsaA12<0.034<0.0341.00 (1.1)<0.0161.34 (1.1)<0.016
SalivaPdB8<0.009<0.0009<0.00090.0019 (1.1)<0.00090.0018 (1.1)
  • a In all cases, P ≤ 0.0004 for immune versus nonimmune controls. Data is expressed as the geometric means of micrograms of immunoglobulin per milliliter (standard error factors are shown in parentheses).

  • b Number in each group in the indicated row except for the last column.

  • c There were eight mice in all groups in this column.

  • d ND, not determined.