Table 2.

Appearance of MAdCAM-1- and ICAM-1-expressing venules throughout the course of a genital MoPn infection

Adhesion molecule and regionMean no. of venules expressing adhesion molecule/mm2 of tissue (± SEM) on day:
07142135
MAdCAM-1
 CV0.04 (0.01)3.90 (1.88)0.50 (0.40)1.14 (0.74)0.04 (0.00)
 UH0.02 (0.00)0.02 (0.00)0.43 (0.36)1.42 (0.88)0.42 (0.39)
 OD0.09 (0.03)0.09 (0.04)1.07 (0.55)0.43 (0.39)0.52 (0.47)
ICAM-1
 CV9.92 (1.25)10.85 (1.74)6.30 (1.12)7.0 (2.87)3.94 (1.3)
 UH0.02 (0.00)4.89 (2.04)9.18 (4.94)a15.2 (2.73)a1.78 (1.58)
 OD0.09 (0.03)0.42 (0.29)5.22 (3.35)9.10 (4.74)1.13 (1.09)
  • a There was a significant increase in the number of venules compared to day 0 values; P < 0.05 by ANOVA and Dunn's post-hoc test.