Table 3.

Affinities of pooled immune chinchilla sera to peptides derived from P5-fimbrin LB1(f) moiety

Antiserum directed against (NTHI strain):AdjuvantMean relative affinity (RU ± SD)a
LB1ps1LB1ps2LB1ps3LB1(2a)LB1(2b)LB1(3)Region 1Region 2LB1(1) region 3Region 4LB1 (40-mer)
Whole OMP (1128)CFA32 ± 372 ± 723 ± 838 ± 240 ± 535 ± 321 ± 925 ± 932 ± 1033 ± 1047 ± 4
Isolated P5-fimbrin (1128)CFA24 ± 932 ± 59 ± 338 ± 333 ± 1056 ± 620 ± 422 ± 1150 ± 541 ± 6 110 ± 15
LB1CFA40 ± 749 ± 1 885 ± 6738 ± 6 211 ± 27 564 ± 5438 ± 1221 ± 10 1,453 ± 7045 ± 14 1,530 ± 63
LPD-LB1(f)2,1,3 A1PO4MPL30 ± 725 ± 917 ± 129 ± 440 ± 663 ± 335 ± 1119 ± 933 ± 1043 ± 1010 ± 5
  • a Values of ≥100 RU are in boldface.