Table 2.

Correlation of IL-12 and IFN-γ production by PBMC treated with Candida organismsa

TreatmentMean concn (pg/ml) ± SD (n = 6)r2P
IL-12IFN-γ
C. albicans SC5314
 Live<10<10
 Heat killed639 ± 1581,281 ± 5860.81<0.01
C. krusei 6258
 Live80 ± 32459 ± 6200.84<0.01
 Heat killed440 ± 1061,201 ± 5700.82<0.01
  • a PBMC were treated with live or heat-killed C. albicans SC5314 and C. krusei6258. Supernatants were collected after incubation for 20 h. Cytokines were measured by ELISA.