Table 1.

Live C. albicans- and C. krusei-induced IL-1β, TNF-α, and MCP-1 production by monocytesa

Monocyte treatmentMean concn (pg/ml) ± SD (n)
IL-1βTNF-αMCP-1
Control<10 (15)<10 (15)2,011 ± 619 (16)
C. albicans SC53141,823 ± 241* (11)5,736 ± 329* (11)7,561 ± 449* (16)
C. krusei62581,885 ± 298* (5)6,546 ± 617* (5)8,581 ± 967* (16)
  • a Human peripheral blood monocytes were treated with live C. albicans SC5314 or C. krusei6258. Supernatants were collected after incubation for 20 h. Cytokines were measured by ELISA. ∗, P < 0.05 versus control.